When is sample size too large




















The two major factors affecting the power of a study are the sample size and the effect size. The larger the sample size is the smaller the effect size that can be detected. The reverse is also true; small sample sizes can detect large effect sizes. While researchers generally have a strong idea of the effect size in their planned study it is in determining an appropriate sample size that often leads to an underpowered study.

This poses both scientific and ethical issues for researchers. A study that has a sample size which is too small may produce inconclusive results and could also be considered unethical , because exposing human subjects or lab animals to the possible risks associated with research is only justifiable if there is a realistic chance that the study will yield useful information. Similarly, a study that has a sample size which is too large will waste scarce resources and could expose more participants than necessary to any related risk.

Thus an appropriate determination of the sample size used in a study is a crucial step in the design of a study. More recent studies analysing the power of published papers has shown that, even still, there are large numbers of papers being published that have insufficient power.

With the availability of sample size software such as nQuery Sample Size and Power Calculator for Successful Clinical Trials which can calculate appropriate sample sizes for any given power such issues should not be arising so often today. Click the image above to view our guide to calculate sample size.

Suppose we ask another people and find that, overall, out of the people own a smartphone. However, our confidence interval for the estimate has now narrowed considerably to Because we have more data and therefore more information, our estimate is more precise.

As our sample size increases, the confidence in our estimate increases, our uncertainty decreases and we have greater precision. This is clearly demonstrated by the narrowing of the confidence intervals in the figure above. If we took this to the limit and sampled our whole population of interest then we would obtain the true value that we are trying to estimate — the actual proportion of adults who own a smartphone in the UK and we would have no uncertainty in our estimate.

Increasing our sample size can also give us greater power to detect differences. Suppose in the example above that we were also interested in whether there is a difference in the proportion of men and women who own a smartphone.

We can estimate the sample proportions for men and women separately and then calculate the difference. When we sampled people originally, suppose that these were made up of 50 men and 50 women, 25 and 34 of whom own a smartphone, respectively. The difference between these two proportions is known as the observed effect size. Is this observed effect significant, given such a small sample from the population, or might the proportions for men and women be the same and the observed effect due merely to chance?

We find that there is insufficient evidence to establish a difference between men and women and the result is not considered statistically significant. It is chosen in advance of performing a test and is the probability of a type I error, i. While existing research has examined the role of social influence on various user behavior, such as product adoption, reviews and purchases, there is a lack of studies on how social influence … Expand.

Use of the p-value as a size-dependent function to address practical differences when analyzing large datasets. View 3 excerpts, cites background. Low sample size and regression: A Monte Carlo approach. This article performs simulations with different small samples considering the regression techniques of OLS, Jackknife, Bootstrap, Lasso and Robust Regression in order to stablish the best approach … Expand. A note on tests for relevant differences with extremely large sample sizes.

View 2 excerpts, references methods and background. View 2 excerpts, references background. Highly Influential. View 3 excerpts, references background. View 2 excerpts, references background and methods. Is the World Really Flat? View 3 excerpts, references background and methods. The problem isn't generally false positives, but true positives -- in situations where people don't want them. People often make the mistaken assumption that statistical significance always implies something practically meaningful.

In large samples, it may not. As sample sizes get very large even very tiny differences from the situation specified in the null may become detectable. This is not a failure of the test, that's how it's supposed to work! When this bothers people it's an indication that hypothesis testing or at least the form of it they were using didn't address the actual research question they had. In some situations this is addressed better by confidence intervals. In others, it's better addressed by calculation of effect sizes.

In other situations equivalence tests might better address what they want. In other cases they might need other things. In large samples, issues like sampling bias can completely dominate effects from sampling variability, to the extent that they're the only thing that you see.

Greater effort is required to address issues like this, because small issues that produce effects that may be very small compared to sampling variation in small samples may dominate in large ones. Again, the impact of that kind of thing is not a problem with hypothesis testing itself, but in the way the sample was obtained, or in treating it as a random sample when it actually wasn't.

Significance level: in very large samples, if you're using the same significance levels that you would in small samples, you're not balancing the costs of the two error types; you can reduce type I error substantially with little detriment to power at effect sizes you care about - it would be odd to tolerate relatively high type I error rates if there's little to gain.

Hypothesis tests in large samples would sensibly be conducted at substantially smaller significance levels, while still retaining good very power why would you have power of



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